Cooley Coleman, Jessica

Fellow - Laboratory Genetics and Genomics

Cooley Coleman, Jessica

Dr. Cooley Coleman joined the Greenwood Genetic Center in 2010 as a Molecular Laboratory Technologist. She was promoted to Lab Manager in 2016. In 2019, she joined the Healthcare Genetics PhD program at Clemson University while continuing to work full time at GGC. After completing her PhD in 2022, she assumed the position of Staff Scientist for the Molecular Diagnostic Laboratory at GGC and began her Laboratory Genetics and Genomics (LGG) fellowship in 2023.

Dr. Cooley Coleman is a board certified technologist in molecular biology through the American Society of Clinical Pathology. She is a member of the Association of Genetic Technologists, the American Society of Human Genetics, and the American College of Medical Genetics and Genomics.

Contact Information

Office (864) 941-8188
Fax (864) 941-8141
[email protected]


  • BS, Biology, Erskine College, 2010
  • PhD, Healthcare Genetics, Clemson University, 2022
  • Molecular Technologist, Molecular Diagnostic Laboratory, Greenwood Genetic Center, 2010-2016
  • Lab Manager, Molecular Diagnostic Laboratory, Greenwood Genetic Center, 2016-2022
  • Staff Scientist, Molecular Diagnostic Laboratory, Greenwood Genetic Center, 2022-2023
  • Laboratory Genetics and Genomic Fellow, Greenwood Genetic Center, 2023-present


  • Washington, C., Stolerman, E., Cooley Coleman, J. A., Jones, J. R., Chen-Deutsch, X. (2023). RNA analysis of intronic variants in the LAMA2 gene detected by whole genome sequencing confirms a rare dual diagnosis of incontinentia pigmenti with limb-girdle muscular dystrophy. Clinical Case Reports. Advance online publication.
  • Cooley Coleman, J. A., Gass, J. M., Srikanth, S., Pauly, R., Ziats, C. A., Everman, D. B., Skinner, S. A., Bell, S., Louie, R. J., Cascio, L., Patterson, W. G., Jones, J. R., Di Donato, N., Stevenson, R. E., Boccuto, L. (2022). Clinical and Functional Characterization of Germline PIK3CA Variants in Patients with PIK3CA-related Overgrowth Spectrum Disorders. Human Molecular Genetics, 32(9), 1457–1465.
  • McGee, S., Rajamanickam, S., Adhikari, S., Falayi, O., Wilson, T., Shayota, B., Cooley Coleman, J. A., Skinner, C., Caylor, R., Stevenson, R., Quaio, C.R. D.C., Wilke, B., Bain, J.M., Anyane-Yeboa, K., Brown, K., Greally, J. Bijlsma, E., Ruivenkamp, C., Politi, K., Arbogast, L., Collard, M., Huggenvik, J., Elsea, S., Jensik, P. (2023). Expansion and mechanistic insights of de novo DEAF1 variants in DEAF1-associated developmental disorders. Human Molecular Genetics, 32(3), 386–401.
  • Cooley Coleman, J. A., Fee, T., Bend, R., Louie, R., Annese, F., Stallworth, J., Worthington, J., Buchanan, C. B., Everman, D. B., Skinner, S., Friez, M., Jones, J. R., Spellicy, C. J. (2022). Mosaicism of Common Pathogenic MECP2 Variants Identified in Two Males with a Clinical Diagnosis of Rett Syndrome. American Journal of Medical Genetics Part A, 188(10), 2988–2998..
  • Sohn, Y. B., Roger, C., Stallworth, J., Cooley Coleman, J. A., Buch, L., Jozwiak, E., Johnson, J. A., Wood, T., Harmatz, P., Pollard, L., Louie, R. J. (2022). RNA analysis of the GALNS transcript reveals novel pathogenic mechanisms associated with Morquio syndrome A. Molecular Genetics and Metabolism Reports, 31 (2022), 100875.
  • Cooley Coleman, J. A., Sarasua, S. M., Moore, H. W., Boccuto, L., Cowan, C. W., Skinner, S. A., & DeLuca, J. M. (2022). Clinical Findings from the Landmark MEF2C-Related Disorders Natural History Study. Molecular Genetics & Genomic Medicine, 10(6), e1919.
  • Cooley Coleman, J. A., Sarasua, S. M., Boccuto, L., Moore, H. W., Skinner, S. A., & DeLuca, J. M. (2021). Comprehensive investigation of the phenotype of MEF2C‐related disorders in human patients: A systematic review. American Journal of Medical Genetics, Part A, 185(12), 3884–3894.
  • Cooley Coleman, J. A., Sarasua, S. M., Boccuto, L., Moore, H. W., Skinner, S. A., & DeLuca, J. M. (2021). Tremors: A concept analysis. Nursing open, 8(5), 2419–2428.
  • Gong B, Li D, Kusko R, Novoradovskaya N, Zhang Y, Wang S, Pabón-Peña C, Zhang Z, Lai K, Cai W, LoCoco JS, Lader E, Richmond TA, Mittal VK, Liu LC, Johann DJ Jr, Willey JC, Bushel PR, Yu Y, Xu C, Chen G, Burgess D, Cawley S, Giorda K, Haseley N, Qiu F, Wilkins K, Arib H, Attwooll C, Babson K, Bao L, Bao W, Lucas AB, Best H, Bhandari A, Bisgin H, Blackburn J, Blomquist TM, Boardman L, Burgher B, Butler DJ, Chang CJ, Chaubey A, Chen T, Chierici M, Chin CR, Close D, Conroy J, Coleman JC, … Xu J (2021). Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions. Genome biology, 22(1), 109.
Mother and son

A Rare Beauty

The lobby of the JC Self Research Institute at GGC was transformed into a garden – of sorts. The art exhibit titled ‘Rare Roses’ consisted of 12 paintings that depict real roses with genetic variations. The series was created by Nicole Shannon, an artist from Greenville. Nicole was inspired by her son, who has a rare genetic disorder, and other individuals with genetic differences. Quinn, now 4, was born with a myriad of health issues and ...

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