Mokashi, Sneha

Staff Scientist

Mokashi, Sneha

Dr. Mokashi joined GGC in 2021 as a postdoc in the laboratory of Dr. Heather Flanagan-Steet and became a staff scientist in the Molecular Diagnostic Laboratory in 2023. Originally from India, she completed her Bachelors and Masters degrees in Biotechnology in 2013. She earned a PhD in Genetics from Clemson University in 2021 working at the Clemson Center for Human Genetics in Greenwood in the laboratories of Drs. Mackay and Anholt.

In the molecular lab, she works on a variety of projects at the bench and computationally with the overall goal of developing new methods and improving current ones to increase diagnostic yield.

Contact Information

Office: (864) 388-1816
[email protected]

Education

  • MSc, Biotechnology, VIT University, India
  • PhD, Genetics, Clemson University, 2021
  • Postdoctoral Associate, Greenwood Genetic Center, 2021-2023
  • Staff Scientist, DNA Diagnostic Laboratory, Greenwood Genetic Center, 2023-present

Selected Publications

  • Mokashi SS, Shankar V, Johnstun JA, Mackay TFC, Anholt RRH. Pleiotropic fitness effects of a Drosophila odorant-binding protein. G3 (Bethesda). 2023 Feb 9;13(2):jkac307. doi: 10.1093/g3journal/jkac307. PMID: 36454098.
  • Radenkovic S, Ligezka AN, Mokashi SS, Driesen K, Dukes-Rimsky L, Preston G, Owuocha LF, Sabbagh L, Mousa J, Lam C, Edmondson A, Larson A, Schultz M, Vermeersch P, Cassiman D, Witters P, Beamer LJ, Kozicz T, Flanagan-Steet H, Ghesquière B, Morava E. Tracer metabolomics reveals the role of aldose reductase in glycosylation. Cell Rep Med. 2023 Jun 20;4(6):101056. doi: 10.1016/j.xcrm.2023.101056. Epub 2023 May 30. PMID: 37257447
  • Baker BM, Mokashi SS, Shankar V, Hatfield JS, Hannah RC, Mackay TFC, Anholt RRH. The Drosophila brain on cocaine at single-cell resolution. Genome Res. 2021 Oct;31(10):1927-1937. doi: 10.1101/gr.268037.120. Epub 2021 May 25. PMID: 34035044
  • Colonna MB, Moss T, Mokashi S, Srikanth S, Jones JR, Foley JR, Skinner C, Lichty A, Kocur A, Wood T, Stewart TM, Casero RA Jr, Flanagan-Steet H, Edison AS, Lyons MJ, Steet R. Functional assessment of homozygous ALDH18A1 variants reveals alterations in amino acid and antioxidant metabolism. Hum Mol Genet. 2023 Feb 19;32(5):732-744. doi: 10.1093/hmg/ddac226. PMID: 36067040
  • Johnstun JA, Shankar V, Mokashi SS, Sunkara LT, Ihearahu UE, Lyman RL, Mackay TFC, Anholt RRH. Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster. Mol Biol Evol. 2021 May 4;38(5):2030-2044. doi: 10.1093/molbev/msab004. PMID: 33560417
  • Mokashi SS, Shankar V, MacPherson RA, Hannah RC, Mackay TFC, Anholt RRH. Developmental Alcohol Exposure in Drosophila: Effects on Adult Phenotypes and Gene Expression in the Brain. Front Psychiatry. 2021 Jul 22;12:699033. doi: 10.3389/fpsyt.2021.699033. eCollection 2021. PMID: 34366927 

 

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