Trisomy 21 FISH, Rule Out Mosaic (Buccal)

Trisomy 21 FISH, Rule Out Mosaic is a cytogenetic test designed to detect varying degrees of mosaicism for chromosome 21 aneuploidy.

Turnaround Time

28 days

CPT Code(s)

88275 x2, 88271 x2, 88291

Cost

$758

• Trisomy 21 also Down syndrome

FISH: Fluorescence in situ hybridization is a molecular cytogenetic technique in which fluorescently labeled DNA probes are hybridized to metaphase spreads or interphase nuclei.

FISH analysis on buccal samples requires a kit provided by the Greenwood Genetic Center. Buccal cells are collected by brush and smeared onto a microscope slide using included instructions. Saliva is not accepted for this test.

Return the labeled slides in the provided packaging via USPS or other transport service at room temperature.