Chromosome Analysis, Routine; Rule Out Mosaic (Blood)
Key Information
Lab:
TAT:
21 days
Price:
$755
CPT Code(s):
88230, 88263, 88285x5, 88291
Test Code:
CBRM
Chromosome Analysis, Routine; Rule Out Mosaic (Blood)
Chromosome mosaicism is defined as the presence of two or more cell lines with different chromosome constitutions in a single individual. Chromosome analysis to rule out mosaicism includes routine karyotyping using G-banded preparations, but additional cells are counted compared to routine chromosome analysis to assess for mosaicism.
Clinical Information
Chromosome analysis on blood can clarify .an atypical number of chromosomes is present at a lower level of mosaicism. This analysis may be indicated if chromosome analysis on a routine count has returned negative/normal or if mosaicism is suspected.
Technical Information
For rule out mosaic chromosome analysis, 50 cells are counted to determine the modal number and a minimum of 5 cells are analyzed for chromosomal abnormalities from G-banded preparations.
Specimen Requirements
The accepted sample type is 3-4 ml of whole blood collected in a sodium heparin (green top) tube. For newborns and small infants, 2-3 ml of blood in a sodium heparin tube is acceptable. Blood kits are available by request.
Transport Instructions
Whole blood should be kept at room temperature and sent by courier or overnight shipping to arrive at the laboratory within 24 hours. Do not freeze or refrigerate the specimen.
Associated Tests
Connect With Our Experts
Call 1-800-473-9411 to speak with our team of laboratory genetic counselors for questions or additional information.
Robin Fletcher, MS, CGC
Falecia Thomas, MS, CGC
Alex Finley, MS, CGC