21
Trisomy 21 FISH, Rule Out Mosaic (Buccal)
Key Information
Lab:
TAT:
28 days
Price:
$758
CPT Code(s):
88275x2, 88271x2, 88291
Test Code:
CT21
Trisomy 21 FISH, Rule Out Mosaic (Buccal)
Trisomy 21 FISH, Rule Out Mosaic is a cytogenetic test designed to detect varying degrees of mosaicism for chromosome 21 aneuploidy.
Please note the standard turnaround time is 28 days, but is reduced to 7 days for infants.
Technical Information
Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique in which fluorescently labeled DNA probes are hybridized to interphase nuclei. FISH should be used in conjunction with G-banded chromosome analysis. FISH can be performed upon request for rapid aneuploidy detection of chromosome 21.
Specimen Requirements
FISH analysis on buccal samples requires a kit provided by the Greenwood Genetic Center. Buccal cells are collected by brush and smeared onto a microscope slide using the kit’s included instructions. Contact the lab to request a test kit. Saliva is not accepted for this test.
Transport Instructions
Return the labeled slides in the provided packaging via USPS or other transport service at room temperature.
Connect With Our Experts
Call 1-800-473-9411 to speak with our team of laboratory genetic counselors for questions or additional information.
Robin Fletcher, MS, CGC
Falecia Thomas, MS, CGC
Alex Finley, MS, CGC