13, 18, 21, X, Y
Trisomy FISH Screen (13,18,21,X,Y) (Blood)
Key Information
Lab:
TAT:
28 days
Price:
$1,250
CPT Code(s):
88230, 88275x2, 88271x4, 88291
Test Code:
CANE
Trisomy FISH Screen (13,18,21,X,Y) (Blood)
Trisomy Screen FISH analysis is a cytogenetic test used to identify aneuplodies involving chromosomes 13, 18, 21, X, and Y. This test should be used in conjunction with G-banded chromosome analysis.
Please note the standard turnaround time is 28 days, but is reduced to 4 days for infants.
Technical Information
Fluorescence in situ hybridization (FISH) is a molecular cytogenetic technique in which fluorescently labeled DNA probes are hybridized to metaphase spreads or interphase nuclei. FISH should be used in conjunction with G-banded chromosome analysis. FISH can be performed upon request for rapid aneuploidy detection of chromosomes 13, 18, 21, X, and Y.
Specimen Requirements
The accepted sample type is 3-4 ml of whole blood collected in a sodium heparin (green top) tube. For newborns and small infants, 2-3 ml of blood in a sodium heparin tube is acceptable. Blood kits are available by request.
Transport Instructions
Blood specimen should be kept at room temperature; do not freeze or refrigerate. Specimen should be sent by courier or overnight mail to arrive at the laboratory the next day.
Connect With Our Experts
Call 1-800-473-9411 to speak with our team of laboratory genetic counselors for questions or additional information.
Robin Fletcher, MS, CGC
Falecia Thomas, MS, CGC
Alex Finley, MS, CGC