Prenatal Screening

What is the difference between a screening test and a diagnostic test?

A screening test (NIPS, first trimester screening, maternal serum screening) adjusts a woman’s risk to have a pregnancy affected with…

What is the fetal fraction?

NIPS analyzes fetal DNA in the mother’s blood. The amount of fetal DNA in the samples is known as the…

Is NIPS covered by my insurance?

Most insurance companies will cover NIPS for a woman of any age as it is the recommended test for all…

Is one NIPS company better than another?

Not necessarily. Most companies use very similar technologies for NIPS. Your genetic counselor or health care provider can help determine…

Is there anyone who should not consider NIPS?

Yes. Women who have undergone an organ transplant are not good candidates for NIPS. This is because small pieces of…

Should I get NIPS if I have a family history of birth defects? What about a family history of cystic fibrosis?

Standard NIPS only screens for Down syndrome (trisomy 21), trisomy 13, trisomy 18, Turner syndrome (monosomy X), Klinefelter syndrome (XXY),…

Should I still consider having NIPS if I don’t have a family history of Down syndrome?

Yes. In over 95% of cases of Down syndrome there is no family history of this condition. The same can…

The NIPS test I had says it has a sensitivity and specificity of 99%. Does that mean my risk is 99% if my screening result is positive?

No. The sensitivity and specificity refer to the ability of the test to accurately call a negative result negative, or…

What is expanded NIPS?

Expanded NIPS refers to NIPS screening tests that look for abnormalities in chromosomes other than 21, 18, 13, X and…

What is Non-Invasive Prenatal Screening (NIPS)?`

NIPS is a screening test to determine if a pregnancy may be at an increased risk for a particular condition,…