Can I have NIPS if I am pregnant with twins?

Yes! However, it is important to note if you have a fraternal twin pregnancy (where the babies each have their own placenta and amniotic sac) the results are less accurate than when used in screening a singleton pregnancy. This is because each twin’s placenta may not release the same amount of chromosome material into the mother’s bloodstream, leading to one twin being either underrepresented or overrepresented. Therefore, for twins, the risk is not reduced as much with a negative NIPS as it would be in a singleton pregnancy. However, NIPS is still the most accurate blood screening test we have for twin pregnancies for these conditions.