Fresh tissue (fetal tissue, amnion, placenta)
Formalin fixed paraffin embedded (FFPE)
Products of Conception should be placed in a sterile container for transport. The specimen must be kept moist, so add tissue culture media or sterile saline if needed.
Fresh tissue: Using sterile technique, obtain a 5 mm biopsy of unmacerated fetal tissue and place in tube containing transport media. If tissue culture media is not available, sterile solutions such as balanced salt solution may be used. The preferred placental tissues are fetal membranes or chorionic villi. If fetal samples are obtained at autopsy, lung, gonad or thymus are preferred for chromosome study.
Cultured tissue: 2-T25 confluent flasks can be sent for analysis.
Extracted DNA is also accepted for this test.
Please note that a maternal sample (4-5 ml of blood collected in a lavender-top/EDTA tube) is strongly recommended to rule out the presence of maternal cell contamination in POC samples. Additional specimen types include: saliva and extracted DNA. An additional charge ($350) will apply.